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variant: search

Gene Variant May Decide Who Smokes and for How Long

(HealthDay News) -- A gene variant that may influence a person's initial response to smoking and lifetime smoking habits has been identified by a team of researchers.

Gene variant boosts risk of fatty liver disease, scientists discover

Researchers at UT Southwestern Medical Center have found that individuals who carry a specific form of the gene PNPLA3 have more fat in their livers and a greater risk of developing liver inflammation. They also found that Hispanics are more likely to carry the gene variant responsible for higher liver-fat content than African-Americans and Caucasians.

Protein Variant Predicts Chemotherapy Response

Researchers at the Moores Cancer Center at the University of California, San Diego (UCSD) in La Jolla have found evidence to explain the varying responses of cancer patients to cisplatin, a common chemotherapy drug that is the first-line therapy for testicular and ovarian cancers. Findings published online on September 3 in the Proceedings of the National Academy of Sciences demonstrated that when a variant version of a key protein that normally causes cell death is active, patients may be resistant to the cancer-killing drug.

Variant Of Mad Cow Disease May Be Transmitted By Blood Transfusions, According To Animal Study

Blood transfusions are a valuable treatment mechanism in modern medicine, but can come with the risk of donor disease transmission. Researchers are continually studying the biology of blood products to understand how certain diseases are transmitted in an effort to reduce this risk during blood transfusions.

Gene variant boosts risk of fatty liver disease, scientists discover

Researchers at UT Southwestern Medical Center have found that individuals who carry a specific form of the gene PNPLA3 have more fat in their livers and a greater risk of developing liver inflammation.

Gene variant boosts risk of fatty liver disease, UT Southwestern scientists discover

DALLAS Sept. 25, 2008 Researchers at UT Southwestern Medical Center have found that individuals who carry a specific form of the gene PNPLA3 have more fat in their livers and a greater risk of developing liver inflammation.

Scientists uncover genetic variant which makes some males prone to infidelity

It sounds like the perfect excuse for a wandering eye — a man's tendency to be unfaithful may be influenced by his genes, research suggests.

Newly discovered gene variant implicated in lupus

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Scientists Identify Gene Variant Invovled in Isolated Cleft Lip

The scientists say the discovery, published online today in the journal "Nature Genetics," could lead to DNA tests to help couples better gauge their risk of having a child with an isolated cleft lip. They also note that the gene variation provides a valuable clue to the complex developmental puzzle of cleft lip. Coupled with other recent gene discoveries and alterations, the scientists say they now can account for about 30 percent of isolated cleft lip. A generation ago, they had yet to identify a single gene alteration.

New public safety robot variant announced

BEDFORD, Mass., Aug. 7 (UPI) -- Massachusetts-based iRobot Corp. has launched a new reconnaissance capable robot technology designed for public safety authorities.

Nikon Shows Hideous 'Black Gold' D60 Variant

Nikon has bought a pot of gold paint and started slapping it around at the D60 factory. The result, as you see above, is a rather tacky looking "special'" edition called the Nikon D60 Black Gold. Is this a gift to the taste-deficient DSLR buyer? No. Nikon expects you to pay an extra $50 for this shiny golden coating, which earns the camera a place in our much coveted "Bling" category.

Cutting The Brakes On The Immune System; Newly Discovered Gene Variant Implicated In Lupus

When a virus or bacteria enters a human body, the immune system revs up to fight and expel the invader. Once the invader is gone, the body puts on the brakes to stop the immune response.

[Short reports] A genome-wide association study identifies an association of a common variant in TERT with susceptibility to idiopathic pulmonary fibrosis

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Scientists identify narcolepsy gene

HONG KONG - Scientists in Japan have identified a gene variant that may be linked to narcolepsy — a condition marked by excessive daytime sleepiness, impaired vision and muscle weakness.

New! Raw Material and Interesting Vehicle Patent Picks

Disclosed is a topical composition containing an isolated polypeptide having the sequence of a stromal-derived factor-1 (SDF-1) variant named stem cell active factor (SCAF) or its functional equivalent, and a cosmetically acceptable carrier. An "isolated polypeptide" refers to a polypeptide that has been separated from other proteins, lipids, and nucleic acids with which it is naturally associated. The composition can further contain an agent selected from the group consisting of an anti-wrinkle herbal extract, a whiting herbal extract, and an anti-acne herbal extract. Applications include improving skin feel and appearance, reducing skin wrinkles and promoting hair growth.

Spelling "truely atrosious," says academic

Fed up with his students' complete inability to spell common English correctly, a British academic has suggested it may be time to accept "variant spellings" as legitimate.

Stuff we like: A dissenting voice in the dissection of the genome

A dissenting voice as the genome is sifted to fight disease. The principal rationale for the $3 billion spent to decode the human genome was that it would enable the discovery of the variant genes that predispose people to common diseases like cancer and Alzheimer’s. But David B. Goldstein of Duke University, a leading young population geneticist known partly for his research into the genetic roots of Jewish ancestry, says the effort to nail down the genetics of most common diseases is not working. -- New York Times

11 ways Android will kick the iPhone?s ass

The T-Mobile G1 isn't an iPhone beater, but Android could beSo Android has arrived with the announcement of the T-Mobile G1. The HTC-manufactured phone certainly has a few nice touches, despite its lack of multi-touch (and with T-Mobile’s particular variant, no accelerometer).

Master Chief crash lands into Fable 2

If you noticed in the details to Fable 2's Collector's Edition, there was an "Otherworldly Bonus" for in-game content. Packaged with the announcement were screenshots, including one conspicuously labeled "Fable2_MasterChief.jpg." Yep, that's not just a coincidence, you're looking at a faux-medieval variant of the Halo superstar. (Halo 3 ending spoiler alert) I guess we know what universe he crash-landed in.

Amazon starts carrying $349.99 Xbox 360 with 60GB hard drive

Two weeks ago, Microsoft cut the price of its Xbox 360 console from $349.99 to $299.99 and announced a new, more expensive model with a higher-capacity hard drive. In short, the 20GB console will keep selling for $299.99 until stocks run out, while a 60GB variant will take its place at $349.99.

DNA-based Vaccine Shows Promise Against Avian Flu

Though it has fallen from the headlines, a global pandemic caused by bird flu still has the United States’ Centers for Disease Control and Prevention on high alert. Yet, to date, the only vaccines that have proven even semi-effective are produced in chicken eggs, take five to six months to prepare and act against a single variant of the H5N1 virus, which mutates incredibly quickly.


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