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On the Effect of Low-Energy Electron Induced DNA Strand Break in Aqueous Solution: A Theoretical Study Indicating Guanine as a Weak Link in DNA

In this theoretical study we have investigated the effect of low-energy electrons attached onto a 3′-guanine monophosphate, 3′-GMP, in the gas phase and in aqueous solution. DFT calculations with B3LYP/DZP++ were performed to study the C3′−O3′ bond break of a 3′-GMP radical anion. Our results show that low-energy electrons, if attached to a 3′-GMP with a neutrally charged phosphate group, can easily induce a C3′−O3′ bond break in both the gas phase and aqueous solution. The activation energy was found here to be 10.3 kcal/mol in the gas phase and, even lower, 5.3 kcal/mol in aqueous solution. In comparison with calculated activation energies for other nucleotides the 3′-GMP has the lowest energy barrier in aqueous solution.

Vertical Solution Providers Leverage Sitecore's Web CMS for Customized Web-Based Solutions

SAN FRANCISCO --(Business Wire)-- Sitecore, the leading provider of .NET Web Content Management System (CMS) and portal software, today announced that vertical solution providers are leveraging Sitecore's Web CMS to develop software solutions targeted toward their specific markets. By incorporating the CMS with vertical-specific applications, these solution providers are able to offer their customers the ability to easily create and manage compelling websites that integrate the business-critical applications that are used in its industry.

Leica / Fujitsu - Image processing system solution for high-end digital SLR cameras

Leica / Fujitsu - Image processing system solution for high-end digital SLR camerasThe co-development of an image processing system solution for high-end digital single-lens reflex (SLR) cameras, to be featured in Leica’s next-generation cameras, has been announced by Leica Camera AG (Leica) and Fujitsu Microelectronics Limited (FML).

Dexterra Pioneers Security Solution for Mobile Business Applications Powered by VeriSign

Bothell, WA - Dexterra Inc., a leading provider of software to automate and manage a mobile workforce, announced today that it is pioneering a two-factor mobile security solution powered by the VeriSign® Unified Authentication Service. Dexterra will provide a first-of-its-kind mobile security solution that will facilitate assured security capabilities for wireless carriers’ and enterprises’ mobile applications, users and devices.

Volante POS Systems Announces Wireless POS Solution For Linux

Toronto based Volante POS Systems has announced a wireless POS solution for Linux, allowing for a flexible and cost effective solution for the hospitality industry.

Fujitsu, Leica Offer New Image Processing Solution

Fujitsu Microelectronics and Leica Camera AG (Leica) have co-developed an image processing system solution for high-end digital single-lens reflex (SLR) cameras. The new solution uses Leica's MAESTRO image processor based on Fujitsu's Milbeaut technology, coupled with its control software.

ISI Adds Metadata Management to Regulatory Solution Suite

BOSTON & WHIPPANY, N.J. --(Business Wire)-- ISI, a leading provider of software and services for the life sciences industry, today announced a new module to its integrated regulatory solution suite at the 2008 RAPS Annual Conference & Exhibition in Boston. ISI Submission Manager (ISM) targets metadata and the relationship between submissions, and allows regulatory teams to easily manage and transfer data between submissions and create powerful reports on submission status based on data from eCTDXPress and ISIPublisher, the company's flagship products to manage eCTD, paper, and non-eCTD electronic submissions (NeES). The suite - which is now integrated through a single platform - allows users to manage all submission types and formats. The "one solution" approach allows companies to streamline submission cycles, reduce process redundancies

Toshiba and Wave Systems Partner to Develop Full Disk Encryption Solution for Mobile PCs

Intel Developer Forum Demonstration Highlights Toshiba’s HDD Encryption Technology and Wave’s Enhanced Trusted Drive Manager Products Irvine, Calif., and Lee, Mass., August 13, 2008 – Toshiba Storage Device Division (SDD), an industry pioneer in small form factor hard disk drives (HDDs), and Wave Systems Corp. (NASDAQ:WAVX), a leader in trusted computing applications and services, today announced an alliance to develop a robust standards-based solution for the secure encryption of data on mobile computing platforms, such as laptop PCs. The full disk encryption solution integrates Toshiba’s HDD encryption technology and an enhanced version of Wave’s EMBASSY Trusted Drive Manager and Remote Administration Server products for the management and administration of encrypting hard drives.

On-Demand EDI and WMS Leaders, SPS Commerce and 3PL Central, Unveil Integrated Solution for Small and Mid-Sized 3PLs

MINNEAPOLIS & OREM, Utah (Business Wire) -- SPS Commerce, the leading provider of SaaS EDI services, and 3PL Central, the first on-demand 3PL Warehouse Management System (WMS) software provider, today unveiled a new solution exclusively for small and mid-sized third party logistics providers (3PLs). The offering combines SPS' robust B2B integration or EDI with 3PL Central's WMS capabilities, both delivered using a Software-as-a-Service (SaaS) or on-demand model to eliminate the need for on-site software, hardware, and expertise. Small and mid-sized 3PLs faced with growing business demands from existing and future customers can leverage this comprehensive solution for improved communications, supply chain visibility, and a streamlined order fulfillment cycle for their customers.

From the X-ray Compact Structure to the Elongated Form of the Full-Length MMP-2 Enzyme in Solution: A Molecular Dynamics Study

Current understanding on the collagenolytic activity performed by the MMPs assumes some degree of relative motion between the catalytic and the hemopexin-like domains of the enzyme. However, all the crystal structures available for the full-length enzymes display a compact arrangement of the protein domains. Herein, we employ Molecular Dynamics simulations to investigate the structure of the full-length MMP-2 enzyme in aqueous solution. This simulation, together with previous experimental results that have been obtained very recently for the MMP-9 and MMP-12 enzymes, gives strong support to the hypothesis that the interdomain dynamics of the MMP enzymes in solution can result in a manifold of conformations including some structures with a large interdomain separation.

CoWare Partners with MontaVista to Accelerate Software Development for Linux-Based Devices

October 3, 2008 -- CoWare, Inc. has partnered with MontaVista Software, Inc. to deliver a joint solution to accelerate the development of Linux-based devices. The solution includes a reference virtual platform running MontaVista Linux and integrating MontaVista development tools, including the DevRocket integrated development environment (IDE). The solution leverages the CoWare Virtual Platform technology, and is designed to accelerate Linux education and the development of Linux support packages and Linux-based electronic devices for markets such as mobile devices, consumer electronics, and networking equipment.

Software AG Extends SOA Management with the Release of webMethods Insight

RESTON, Va. --(Business Wire)-- Software AG, a global leader in business infrastructure software, today announced the availability of webMethods Insight, a new solution for the run-time management of heterogeneous SOA environments. The release builds upon a new strategic OEM partnership with Progress Software for the Actional(R) line of enterprise-class SOA management products. webMethods Insight provides enterprises with a proven, best-of-breed solution for the monitoring, policy enforcement and provisioning of run-time services. With deep integration with CentraSite(TM), a top-ranked solution for service-oriented architecture (SOA) governance available from Software AG, webMethods Insight helps users optimize service performance across the entire SOA lifecycle.

CoWare, MontaVista Speed Software Development of Linux Devices

CoWare®, Inc., the leading supplier of platform-driven electronic system-level (ESL) design software and services, announced that it has partnered with MontaVista® Software, Inc., the leader in embedded Linux® commercialization, to deliver a joint solution to accelerate the development of Linux-based devices. The solution includes a reference virtual platform running MontaVista Linux and integrating MontaVista development tools, including the DevRocket integrated development environment (IDE). The solution leverages the CoWare Virtual Platform technology, and is designed to accelerate Linux education and the development of Linux support packages and Linux-based electronic devices for markets such as mobile devices, consumer electronics, and networking equipment.

CoWare and MontaVista Deliver Joint Solution to Accelerate Software Development for Linux-based Devices

Solution Enables Companies to Accelerate Linux Education, Linux Support Package Development and Linux-based Device Development, Integration and Test Using CoWare Virtual Platforms

CoWare and MontaVista Deliver Joint Solution to Accelerate Software Development of Linux-based Devices

Solution Enables Companies to Accelerate Linux Education, Linux Support Package Development and Linux-based Device Development, Integration and Test Using CoWare Virtual Platforms

Vertical Solution Providers Leverage Sitecore's Web CMS for Customized Web-Based Solutions

SAN FRANCISCO - Sitecore, the leading provider of .NET Web Content Management System (CMS) and portal software, today announced that vertical solution providers are leveraging Sitecore’s

Virtual Observer Call Recording Solution Locks Down Security for Valuable Customer Data and Helps Meet PCI and HIPAA Compliance

Virtual Observer Call Recording Solution Locks Down Security for Valuable Customer Data and Helps Meet PCI and HIPAA Compliance

CoreTrace's Application Whitelisting Solution Stops 100 Percent of Computer Viruses During DEFCON 16 "Race-to-Zero" Competition

CoreTrace's Application Whitelisting Solution Stops 100 Percent of Computer Viruses During DEFCON 16 "Race-to-Zero" Competition

PDA based professional surveying solution for building surveys

PDA based professional surveying solution for building surveys - The goal of the new product developed by the company OrthoGraph is the highest achievable support of floor-plan (graphical) surveying of facilities. Using this software the measurements are produced in electronic format right on the spot, while using all possible data-entry equipments and providing automatic control on the values. The system is able to manage large data amounts rapidly, to connect with databases, supports teamwork and - for making the data acquisition easier - can handle laser distance meters or barcode readers (e.g. for inventory purposes).

Dexterra Pioneers Security Solution for Mobile Business Applications Powered by VeriSign

pioneering a two-factor mobile security solution powered by the VeriSign? Unified Authentication

CoreTrace's Application Whitelisting Solution Stops 100 Percent of Computer Viruses During DEFCON 16 "Race-to-Zero" Competition

CoreTrace's Application Whitelisting Solution Stops 100 Percent of Computer Viruses During DEFCON 16 "Race-to-Zero" Competition

Kuka launches robotic palletising solution

Kuka has unveiled its latest high-speed palletising solution using a standard robot that is capable of rapidly packing 25kg sacks as fast as 24 units a minute.

Soundwin--the Outstanding VoIP Solution Provider Presents the Advanced VPN Devices

Home arrow Organizational arrow Soundwin--the Outstanding VoIP Solution Provider Presents the Advanced VPN Devices

CoWare and MontaVista Deliver Joint Solution to Accelerate Software Development of Linux-based Devices

TMCNet: CoWare and MontaVista Deliver Joint Solution to Accelerate Software Development of Linux-based Devices

Innaworks Launches Automated Java Conversion Solution For Windows Mobile at CTIA Wireless I.T. and Entertainment at Booth #324

TMCNet: Innaworks Launches Automated Java Conversion Solution For Windows Mobile at CTIA Wireless I.T. and Entertainment at Booth #324

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