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The Siderocalin/Enterobactin Interaction: A Link between Mammalian Immunity and Bacterial Iron Transport1

The Siderocalin/Enterobactin Interaction: A Link between Mammalian Immunity and Bacterial Iron Transport

Die Hard DNA

Geneticists uncovered portions of mammalian DNA that mutated very little over the course of human evolution, roughly 80 to 100 million years long. The tiny snippets are thought to be more than 300 times less likely to disappear over the years. The find only further goes to show how little medicine actually knows about the human genome and its role. As of yet, no one has been able to determine exactly what the little piece of DNA actually does or why it's so resilient to outside mutagen factors.

Leishmaniasis Parasites Evade Death By Exploiting Immune Response To Sand Fly Bites

Cutaneous leishmaniasis, a disease characterized by painful skin ulcers, occurs when the parasite Leishmania major, or a related species, is transmitted to a mammalian host by the bite of an infected sand fly. In a new study from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, scientists have discovered L. major does its damage by not only evading but also by exploiting the body's wound-healing response to sand fly bites, as reported in the August 15 issue of Science.

Leishmaniasis parasites evade death by exploiting the immune response to sand fly bites

Cutaneous leishmaniasis, a disease characterized by painful skin ulcers, occurs when the parasite Leishmania major, or a related species, is transmitted to a mammalian host by the bite of an infected sand fly. In a new study from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, scientists have discovered L. major does its damage by not only evading but also by exploiting the body's wound-healing response to sand fly bites, as reported in the August 15 issue of Science.

Mysterious DNA Found to Survive Eons of Evolution

The mystery DNA spippets are about 300 times less likely than other regions of the genome to be lost during the course of mammalian evolution. Credit: Dreamstime

NHGRI supports sequencing for $1,000 genome

BETHESDA, Md.—The National Human Genome Research Institute (NHGRI) plans to support a number of researchers under its Revolutionary Genome Sequencing Technologies grant program, focusing on technologies and methods that can help to bring the cost of sequencing a mammalian-sized genome down to around $1,000 by around the year 2014.

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