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janus: search

Nanotechnology zippers for membranes

(Nanowerk Spotlight) Nanotechnology researchers have appropriated the name of Janus - the Roman god of gates and doorways, usually depicted with two heads looking in opposite directions - to name a class of amphiphilic (i.e. containing both hydrophobic and hydrophilic portions) nanoparticles composed of two fused hemispheres, each made from a different substance. Their particular structure makes Janus particles an intriguing subject for exploring novel anti-cancer therapies where they, for instance, carry two different and complementary medicines. In a novel use of Janus particles, researchers have now isolated a means of using them to make 're-sealable' pores in lipid bilayer membranes. Described in another way, the localization of the nanoparticles in the pore can be thought of as the placement of a zipper, which allows a specific slit

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