chromosome: search

Enzyme Helps Males Make Up For Their X Chromosome Shortage

Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the EMBL-European Bioinformatics Institute (EMBL-EBI) in Hinxton, UK, have revealed new insights into how sex chromosomes are regulated. A chromatin modifying enzyme helps compensate for the fact that males have only one copy of the sex chromosome X, while females have two. The enzyme distinguishes between male and female sex chromosomes in fruit flies and binds to different locations on the male and female X chromosome, the scientists have recently reported in the journal Cell. The evolutionarily conserved enzyme is also found in humans.

X chromosome exposed

An enzyme that binds differently to male and female sex chromosomes helps males to make up for their X chromosome shortage

deCODE Discovers Novel Genetic Links Between Pigmentation Traits and Risk of Skin Cancer

and the U.S. expand upon the company's recent findings in the genetics of pigmentation traits in people of European descent, and demonstrate that certain of these common variants also confer risk of two types of skin cancer. In the first paper, utilizing genomic analysis of nearly 8,500 Icelandic and Dutch participants, the deCODE team identified a novel, tightly-linked pair of single-letter variants (SNPs) near the ASIP (agouti signaling protein) gene on chromosome 20 that greatly increase the likelihood of an individual being prone to freckles and sunburn. A SNP in the TYR (tyrosinase) gene on chromosome 11, previously linked by deCODE to eye color, was here shown also to confer susceptibility to sunburn. Both ASIP and TYR are known to play a role in pigmentation.

deCODE Discovers Novel Genetic Links Between Pigmentation Traits and Risk of Skin Cancer

REYKJAVIK, Iceland, May 18 /PRNewswire/ -- In two papers published today, deCODE scientists and academic colleagues from Europe and the U.S. expand upon the company's recent findings in the genetics of pigmentation traits in people of European descent, and demonstrate that certain of these common variants also confer risk of two types of skin cancer. In the first paper, utilizing genomic analysis of nearly 8,500 Icelandic and Dutch participants, the deCODE team identified a novel, tightly-linked pair of single-letter variants (SNPs) near the ASIP (agouti signaling protein) gene on chromosome 20 that greatly increase the likelihood of an individual being prone to freckles and sunburn. A SNP in the TYR (tyrosinase) gene on chromosome 11, previously linked by deCODE to eye color, was here shown also to confer susceptibility to sunburn.

deCODE Discovers Novel Genetic Links Between Pigmentation Traits and Risk of Skin Cancer

REYKJAVIK, Iceland, May 18 /PRNewswire/ -- In two papers published today, deCODE scientists and academic colleagues from Europe and the U.S. expand upon the company's recent findings in the genetics of pigmentation traits in people of European descent, and demonstrate that certain of these common variants also confer risk of two types of skin cancer. In the first paper, utilizing genomic analysis of nearly 8,500 Icelandic and Dutch participants, the deCODE team identified a novel, tightly-linked pair of single-letter variants (SNPs) near the ASIP (agouti signaling protein) gene on chromosome 20 that greatly increase the likelihood of an individual being prone to freckles and sunburn. A SNP in the TYR (tyrosinase) gene on chromosome 11, previously linked by deCODE to eye color, was here shown also to confer susceptibility to sunburn.

deCODE Discovers Novel Genetic Links Between Pigmentation Traits and Risk of Skin Cancer

REYKJAVIK, Iceland, May 18 /PRNewswire/ -- In two papers published today, deCODE scientists and academic colleagues from Europe and the U.S. expand upon the company's recent findings in the genetics of pigmentation traits in people of European descent, and demonstrate that certain of these common variants also confer risk of two types of skin cancer. In the first paper, utilizing genomic analysis of nearly 8,500 Icelandic and Dutch participants, the deCODE team identified a novel, tightly-linked pair of single-letter variants (SNPs) near the ASIP (agouti signaling protein) gene on chromosome 20 that greatly increase the likelihood of an individual being prone to freckles and sunburn. A SNP in the TYR (tyrosinase) gene on chromosome 11, previously linked by deCODE to eye color, was here shown also to confer susceptibility to sunburn.

deCODE Discovers Novel Genetic Links Between Pigmentation Traits and Risk of Skin Cancer

REYKJAVIK, Iceland, May 18 /PRNewswire/ -- In two papers published today, deCODE scientists and academic colleagues from Europe and the U.S. expand upon the company's recent findings in the genetics of pigmentation traits in people of European descent, and demonstrate that certain of these common variants also confer risk of two types of skin cancer. In the first paper, utilizing genomic analysis of nearly 8,500 Icelandic and Dutch participants, the deCODE team identified a novel, tightly-linked pair of single-letter variants (SNPs) near the ASIP (agouti signaling protein) gene on chromosome 20 that greatly increase the likelihood of an individual being prone to freckles and sunburn. A SNP in the TYR (tyrosinase) gene on chromosome 11, previously linked by deCODE to eye color, was here shown also to confer susceptibility to sunburn.

Y Chromosome Points To Clues About Athapaskan Migration

A large-scale genetic study of native North Americans offers new insights into the migration of a small group of Athapaskan natives from their subarctic home in northwest North America to the southwestern United States. The migration, which left no known archaeological trace, is believed to have occurred about 500 years ago.

Y chromosome study sheds light on Athapaskan migration to southwest US

Dark areas on this North American map represent the distribution of the Athapaskan language family. Modified from http:en.wikipedia.orgwikiImage:Na-Denelangs.png with reference to Campbell (1997) and Goddard (1996).

Y chromosome study sheds light on Athapaskan migration to southwest US

Geronimo, a well-known military leader of the Chiricahua Apache in New Mexico, may have been a descendant of subarctic Athapaskan immigrants.

Multiple Regions Of Chromosome 8 Found To Be Associated With Different Cancers

Broadband Service Provider Trident SR Sdn. Bhd.

Athapaskan Migration To Southwest U.S. Illuminated With Y Chromosome Study

A large-scale genetic study of native North Americans offers new insights into the migration of a small group of Athapaskan natives from their subarctic home in northwest North America to the southwestern United States. The migration, which left no known archaeological trace, is believed to have occurred about 500 years ago.

Broken DNA Must Find Right Partners Quickly Amid Repairs

A gene called ATM suppresses DNA break-induced chromosome translocations, which are present in some cancers and predict the success or failure of therapies for those cancers. The research, described in this week's issue of Nature, was performed at The University of Texas Health Science Center at San Antonio.

Enzyme key to 'sister act' that maintains genome stability

Keeping the genome stable is a "sister act" of matched chromatids – the pairs of the double helix DNA molecule that exist during the chromosome duplication in the S phase of the cell cycle.

Enzyme Key To 'Sister Act' That Maintains Genome Stability

Keeping the genome stable is a "sister act" of matched chromatids -- the pairs of the double helix DNA molecule that exist during the chromosome duplication in the S phase of the cell cycle.

Enzyme key to 'sister act' that maintains genome stability

Keeping the genome stable is a "sister act" of matched chromatids the pairs of the double helix DNA molecule that exist during the chromosome duplication in the S phase of the cell cycle.

Evolution Of An Imprinted Domain In Mammals

The normal human genome contains 46 chromosomes: 23 from the mother and 23 from the father. Thus, you have two copies of every gene (excluding some irregularity in the pair of sex chromosomes). In general, which parent contributes a chromosome has no effect on the expression of the genes found on it. Exceptions to this rule are caused by "genomic imprinting"--modification of DNA, which means that gene expression is influenced by which parent the gene came from. A new paper investigates the evolution of genomic imprinting in a specific region of the mammalian genome. The work, by Anne Ferguson-Smith and colleagues in the UK and Australia, shows that different regions became imprinted at different times during mammalian evolution.

Quantum dots shed light on protein workload

Cell division is essential to life, but the mechanism by which emerging daughter cells organize and divvy up their genetic endowments is little understood. In a new study, researchers at the Univ. of Illinois and Columbia Univ. report on how a key motor protein orchestrates chromosome movements at a critical stage of cell division.

deCODE Discovers Novel Genetic Links Between Pigmentation Traits and Risk of Skin...

deCODE Discovers Novel Genetic Links Between Pigmentation Traits and Risk of Skin Cancer Discoveries help to detail how some fair coloring traits contribute to risk of skin cancer; findings will be integrated into the deCODEme(TM) service REYKJAVIK, Iceland, May 18 /PRNewswire/ -- In two papers published today, deCODE scientists and academic colleagues from Europe and the U.S. expand upon the company's recent findings in the genetics of pigmentation traits in people of European descent, and demonstrate that certain of these common variants also confer risk of two types of skin cancer. In the first paper, utilizing genomic analysis of nearly 8,500 Icelandic and Dutch participants, the deCODE team identified a novel, tightly-linked pair of single-letter variants (SNPs) near the ASIP (agouti signaling protein) gene on chromosome 20 that grea

Search took 0.02 seconds.