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Nanocantilevers image nanoparticles in cells

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Scientists Use Virus To Reprogram Adult Cells In Mice

n2hightech writes "Harvard University scientists figured out how to activate a trio of dormant genes that commanded non-insulin producing pancreas cells to switch to the Beta type insulin producing cells. The method uses an engineered virus to infect the cells and deliver special proteins that activate the dormant genes. This technology has the potential to make all stem cell based methods obsolete because it does not pose the risk of rejection and cancer associated with stem cells. A simple injection into the area where cells need to be reprogrammed is all that is required." Gospodin adds a link to coverage at the Washington Post.

Researchers Modify T-Cells, Make Them HIV Resistant

DieNadel writes to share that naturally occurring proteins called "zinc fingers" are being used in a new approach to AIDS treatment. Using modified T-Cells with the zinc fingers, researchers at the Pennsylvania School of Medicine have shown a reduction in viral load in mice. "'By inducing mutations in the CCR5 gene using zinc finger proteins, we've reduced the expression of CCR5 surface proteins on T cells, which is necessary for the AIDS virus to enter these immune system cells,' explains first author Elena Perez, MD, PhD, Assistant Professor of Pediatrics at Penn. 'This approach stops the AIDS virus from entering the T cells because it now has an introduced error into the CCR5 gene.'"

Skin Cells Produce Library of Diseased Stem Cells

WASHINGTON (Reuters) – U.S. stem cell experts have produced a library of the powerful cells using ordinary skin and bone marrow cells from patients, and said Thursday they would share them freely with other researchers.

Injections To Replace Heart Surgery?

chareverie writes "Researchers at Harvard University have been working towards a goal of replacing some types of heart surgery with injections of cells that would grow into blood vessels for damaged hearts. The cells that would be used are progenitor cells obtained from the blood or bone marrow, as opposed to stem cells that are obtained from human embryos. The research team was successful with their tests on growing heart blood vessels in mice. Joyce Bishoff, an associate professor of medicine at Harvard and senior author of the report, says, 'Our next goal down the line is to use them in humans.' She also notes that more studies need to be done on animals to see how these cells would react and behave with other types of tissues. A similar human experiment was done two years ago in Germany, during which a few people from a group of 75 he

High-Efficiency, Flexible, High-Stability Solar Cells

Nanotechnology-based hybrid nanocrystal inorganic thinfilm photovoltaics combine the best features of solar cells constructed from bulk thin-film silicon and from polymer solar cells. The colloidal nanocrystal (NC) cell technology offered here allows the production of air-stable solar cells processed using solution phase methods. The technology simplifies fabrication under ambient conditions, thus expanding the range of flexible or conformal substrates that can be used.

High-Efficiency, Flexible, High-Stability Solar Cells

Nanotechnology-based hybrid nanocrystal inorganic thinfilm photovoltaics combine the best features of solar cells constructed from bulk thin-film silicon and from polymer solar cells. The colloidal nanocrystal (NC) cell technology offered here allows the production of air-stable solar cells processed using solution phase methods. The technology simplifies fabrication under ambient conditions, thus expanding the range of flexible or conformal substrates that can be used.

Like Eavesdropping At A Party: How A Tiny Protein Senses All The Communications In A Cell

Cells rely on calcium as a universal means of communication. For example, a sudden rush of calcium can trigger nerve cells to convey thoughts in the brain or cause a heart cell to beat. A longstanding mystery has been how cells and molecules manage to appropriately sense and respond to the variety of calcium fluctuations within cells.

Like Eavesdropping at a Party: Scientists Discover How a Tiny Protein Senses All the Communications in a Cell

Cells rely on calcium as a universal means of communication. For example, a sudden rush of calcium can trigger nerve cells to convey thoughts in the brain or cause a heart cell to beat. A longstanding mystery has been how cells and molecules manage to appropriately sense and respond to the variety of calcium fluctuations within cells.

Adult Stem Cells Activated In Mammalian Brain

Adult stem cells originate in a different part of the brain than is commonly believed, and with proper stimulation they can produce new brain cells to replace those lost to disease or injury, a study by UC Irvine scientists has shown.

Solar Cells - Made In a Pizza Oven

stylemessiah writes "The winner of several Eureka Science Awards in Australia is a crafty chick who devised a way to create solar cells cheaply using a pizza oven, nail polish and an inkjet printer. This was developed to address the high cost of cells and in particular for the world's poorest regions. She wanted to give the ~2 billion people around the world who don't have electricity the gift of light and cheap energy. This could have profound (and a good profound) implications for education and health in those in the poorest regions in the world. And it all started with her parents giving her a solar energy kit when she was 10 ..."

UNC researcher aims to 'unmask' cancer cells to trigger body's immune system

CHAPEL HILL — Cancer cells are deadly traitors, good cells gone bad. They evade the body's defense systems, passing themselves off as organisms that pose no threat.

Despite Breakthroughs, Embryonic Stem Cells Still Needed

The transformation of pancreas cells from one type to another has been hailed as a breakthrough: until now, such tricks required of scientifically -- and sometimes ethically -- tricky stem cells.

Immune Response To Human Embryonic Stem Cells In Mice Suggests Human Therapy May Face Challenge

Human embryonic stem cells trigger an immune response in mice, researchers from the Stanford University School of Medicine report. The finding suggests that the effectiveness of human therapies derived from the cells could be limited unless ways are found to dampen the rejection response.

Protein's role in stem cells fate studied

Notch protein in human embryonic stem cells helps cells decide their own fate, which may be useful in stem cell therapy development, U.S. researchers said.

Mouse embryonic stem cells build a heart

U.S. researchers have shown mouse embryonic stem cells can build the heart, thereby moving science closer to heart disease treatments using human stem cells.

Protein's role in stem cells fate studied

Baltimore -- Notch protein in human embryonic stem cells helps cells "decide" their own fate, which may be useful in stem cell therapy development, U.S. researchers said.

Protein's role in stem cells fate studied

BALTIMORE, July 22 (UPI) -- Notch protein in human embryonic stem cells helps cells "decide" their own fate, which may be useful in stem cell therapy development, U.S. researchers said.

Protein Key To Control, Growth Of Blood Cells

New research sheds light on the biological events by which stem cells in the bone marrow develop into the broad variety of cells that circulate in the blood. The findings may help improve the success of bone marrow transplants and may lead to better treatments for life-threatening blood diseases.

Protein key to control, growth of blood cells

New research sheds light on the biological events by which stem cells in the bone marrow develop into the broad variety of cells that circulate in the blood. The findings may help improve the success of bone marrow transplants and may lead to better treatments for life-threatening blood diseases.

SiC quantum dots image live cells

Researchers in France have made the first, chemically inert, biocompatible silicon carbide quantum dots for fluorescence imaging of living cells. The result is a major advance since all quantum dots used for imaging so far were toxic to cells.

Identification of protein able to stimulate production of T-cells

A team of Canadian and Finnish scientists has identified a protein able to stimulate the production of T-cells, the white blood cells involved in the recognition and the elimination of infectious agents. The discovery by researchers of the Institute for Research in Immunology and Cancer (IRIC) at the Université de Montréal in Canada and the University of Oulu in Finland – published in the latest edition of the journal Immunity – could help to combat age-related declines in immune response.

Combating Age-related Immune-response Decline: Protein Found To Stimulate Production Of T-cells

A team of Canadian and Finnish scientists has identified a protein able to stimulate the production of T-cells, the white blood cells involved in the recognition and the elimination of infectious agents. The discovery by researchers of the Institute for Research in Immunology and Cancer (IRIC) at the Université de Montréal in Canada and the University of Oulu in Finland could help to combat age-related declines in immune response.

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