Life shortening telomere gene discovered: related news

Life-shortening telomere gene discovered

PARIS: Some people carry a genetic variant is responsible for short telomeres - caps at the end of DNA that control ageing - and it could shave three or four years off their life, according to a new study.

A ligand-dependent hammerhead ribozyme switch for controlling mammalian gene expression

The possibility to externally control gene expression is of fundamental importance in both basic and applied life sciences. Although there are some techniques available to regulate expression in mammalian cells, they rely on the presence of ligand-sensing transcription factors, making it necessary to generate cell lines or organisms that stably express these regulatory factors. In recent years, mechanisms relying on direct RNA-ligand interactions for controlling gene expression have been both discovered in nature and engineered artificially. Among the latter, RNA switches relying on catalytically active RNA have been described. In principle, ligand-dependent triggering of mRNA self-cleavage should be a universal mechanism in order to control gene expression in a variety of organisms.

Second Life Tries To Backpedal On the GPL

GigsVT writes "The Second Life viewer has been available under the GPL for three years. Linden Lab, the maker of Second Life, recently released a 'third party viewer' policy that all but erases the freedoms granted under the GPL. It includes such draconian measures as 'You agree to update or delete at our request any data that you have received from Second Life or our servers and systems using a Third-Party Viewer,' 'You must not mask IP or MAC addresses' (reported to the server), 'you must have a published privacy policy explaining your practices regarding user data,' and 'You acknowledge and agree that we may require you to stop using or distributing a Third-Party Viewer for accessing Second Life if we determine that there is a violation.'"

Cancer: "Primitive" Gene Discovered Researchers Prove Cancer Gene In Ancestral Metazoan

To find the causes for cancer, biochemists and developmental biologists at the University of Innsbruck, Austria, retraced the function of an important human cancer gene 600 million years back in time. For the first time, they have identified the oncogene myc in a fresh water polyp and they have shown that this oncogene has similar biochemical functions in ancestral metazoan and in humans. The scientists published their findings in PNAS.

Cancer: ?Primitive? Gene Discovered - Researchers show cancer gene in ancestral metazoan

To find the causes for cancer, biochemists and developmental biologists at the University of Innsbruck, Austria, retraced the function of an important human cancer gene 600 million years back in time. For the first time, they have identified the oncogene myc in a fresh water polyp and they have shown that this oncogene has similar biochemical functions in ancestral metazoan and in humans. The scientists published their findings in PNAS.

Targeted gene therapy beneficial to mice with spinal muscular atrophy

Spinal muscular atrophy (SMA) is a neuromuscular disease characterized by progressive muscle wasting and weakness. The severity of the disease varies between individuals, with the clinical spectrum ranging from early infant death to normal adult life with only mild weakness. Currently, there are no effective therapies. As SMA is caused by mutations in the SMN1 gene that result in a lack of SMN protein, gene therapy provides one possible treatment strategy. Marco Passini and colleagues, at Genzyme Corporation, Framingham, now provide hope that this therapeutic approach might one day be possible by showing that in a severe mouse model of SMA they can substantially improve muscle strength, coordination, and locomotion by injecting the gene-carrying therapeutic directly into the brain and spinal cord of newborn mice.

Life beyond our universe: Physicists explore the possibility of life in universes with laws different from our own

(PhysOrg.com) -- Whether life exists elsewhere in our universe is a longstanding mystery. But for some scientists, there?s another interesting question: could there be life in a universe significantly different from our own?

One gene lost = one limb regained? Scientists demonstrate mammalian regeneration through a single gene deletion

A quest that began over a decade ago with a chance observation has reached a milestone: the identification of a gene that may regulate regeneration in mammals. The absence of this single gene, called p21, confers a healing potential in mice long thought to have been lost through evolution and reserved for creatures like flatworms, sponges, and some species of salamander.

Life Sciences: Fudan University, Gene Research Center publishes research in life sciences

New investigation results, 'Laminarin-mediated targeting to Dectin-1 enhances antigen-specific immune responses,' are detailed in a study published in Biochemical and Biophysical Research Communications. According to recent research published in the journal Biochemical and Biophysical Research Communications, "It has immense potential for immunotherapy and vaccination to target antigens to antigen-presenting cells (APCs). Here we described a method for delivering whole protein antigens to APCs via carbohydrate-mediated targeting of Dectin-1, which is a C-type lectin and mainly expresses on subpopulations of dendritic cells and macrophages."

Gene discovery may have profound impact

British researchers have identified a gene variant that may be linked to ageing. The discovery of the gene could allow doctors to make an early diagnosis of people who are prone to ageing more rapidly than usual, so they can prescribe courses of treatment that will allow such persons to extend their life by avoiding certain health risks and taking certain medicines.

Scientists Discover Gene Behind Pain

Scientists have discovered a gene which may help explain why some people are more sensitive to and less able to tolerate pain.

Dr Geoffrey Woods, of Cambridge University, said that discovery of a gene responsible for pain could greatly increase the ability to conquer and control it.

Cancer: ?Primitive? Gene Discovered - Researchers show cancer gene in ancestral metazoan

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Artificial Life, Inc. Mandates Close Brothers Seydler Bank AG as Its Designated Sponsor in Germany

FRANKFURT, Germany, HONG KONG and LOS ANGELES, Feb. 16, 2010 (GLOBE NEWSWIRE) -- Artificial Life, Inc. (OTCBB:ALIF), a leading provider of award-winning mobile 3G technology and applications, today announced that it has mandated Close Brothers Seydler Bank AG, the German Small and Mid-Caps specialist bank, as its Designated Sponsor (market maker) for its planned upgraded listing in the Entry Standard market segment in Germany later this year. Artificial Life, Inc. shares have been traded for several years in the over-the-counter market in Germany, and the Company intends to upgrade its German trading activities to the Entry Standard segment of the Frankfurt Stock Exchange. The Company's current United States over the counter listing and trading of Artificial Life's shares in the United States will not be affected by this anticipated chang

Discovery Of Gene That Affects Susceptibility To TB And Clues To How It Works

University of Washington (UW) researchers have identified a gene involved in susceptibility and resistance to tuberculosis. This same gene, they have found, has a role in the severity of leprosy, which is caused by a related pathogen. The researchers also have learned why this gene is important for susceptibility.

Johnny Cash: LIFE's Best Photos

Nov. 21, 1969: The cover of LIFE magazine features Johnny Cash, who'd just released his "At San Quentin," his second live album recorded before inmates (the first, "At Folsom Prison," was his breakthrough). Wrote LIFE of the king of country music, "He has been fascinated by railroads since childhood when his father would hop freights to look for work." Click through this gallery for more photos and quotes from this classic LIFE cover story.

Structureless Space Telescope Could Look For Life Around Other Stars

Goes color A big aspiration for astronomers is to identify life on planets orbiting other stars. Thanks to NASA's Kepler mission we will know about the statistical abundance of Earthlike worlds in our galaxy in just a few years. But confirming that other worlds are actually inhabited (not just inhabitable) could take decades. And, finding just one such planet won't be enough. We'll need to survey at least several nearby exo-Earths to convince ourselves we are actually seeing the biosignatures of life. Accomplishing this will be a Herculean task. Huge space telescopes are needed to harvest the feeble glow of an exo-Earth. That's because the light needs to be dissected into a spectrum that yields the chemical fingerprint of life processes. Probably nothing smaller than a 16-meter space telescope would be needed.

Mammalian Regeneration Through A Single Gene Deletion Demonstrated By Wistar Scientists

A quest that began over a decade ago with a chance observation has reached a milestone: the identification of a gene that may regulate regeneration in mammals. The absence of this single gene, called p21, confers a healing potential in mice long thought to have been lost through evolution and reserved for creatures like flatworms, sponges, and some species of salamander. In a report published in the Proceedings of the National Academy of Sciences, researchers from The Wistar Institute demonstrate that mice that lack the p21 gene gain the ability to regenerate lost or damaged tissue.

Scientists Demonstrate Mammalian Regeneration Through a Single Gene Deletion

Newswise — A quest that began over a decade ago with a chance observation has reached a milestone: the identification of a gene that may regulate regeneration in mammals. The absence of this single gene, called p21, confers a healing potential in mice long thought to have been lost through evolution and reserved for creatures like flatworms, sponges, and some species of salamander. In a report published today in the Proceedings of the National Academy of Sciences, researchers from The Wistar Institute demonstrate that mice that lack the p21 gene gain the ability to regenerate lost or damaged tissue.

Tufts University, Health Sciences: Researchers develop new tool for gene delivery

Researchers at Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts have developed a new tool for gene therapy that significantly increases gene delivery to cells in the retina compared to other carriers and DNA alone, according to a study published in the January issue of The Journal of Gene Medicine. The tool, a peptide called PEG-POD, provides a vehicle for therapeutic genes and may help researchers develop therapies for degenerative eye disorders such as retinitis pigmentosa and age-related macular degeneration.

Gene discovered for newly recognized disease in Amish children

The gene for a newly recognized disease has been identified thanks to the determination of an Amish father and the clinical skills and persistence of Indiana University and Riley Hospital for Children physicians in collaboration with physicians and researchers at the Clinic for Special Children in Lancaster County, Penn., which specializes in disorders of the Amish.

Gene discovered for newly recognized disease in Amish children

The gene for a newly recognized disease has been identified thanks to the determination of an Amish father and the clinical skills and persistence of Indiana University and Riley Hospital for Children physicians in collaboration with physicians and researchers at the Clinic for Special Children in Lancaster County, Penn., which specializes in disorders of the Amish.

Gene Discovered for Newly Recognized Disease in Amish Children

INDIANAPOLIS — The gene for a newly recognized disease has been identified thanks to the determination of an Amish father and the clinical skills and persistence of Indiana University and Riley Hospital for Children physicians in collaboration with physicians and researchers at the Clinic for Special Children in Lancaster County, Penn., which specializes in disorders of the Amish.

Gene discovered for newly recognized disease in Amish children

INDIANAPOLIS -- The gene for a newly recognized disease has been identified thanks to the determination of an Amish father and the clinical skills and persistence of Indiana University and Riley Hospital for Children physicians in collaboration with physicians and researchers at the Clinic for Special Children in Lancaster County, Penn., which specializes in disorders of the Amish.

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