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GSC Aims to Unite Genome Sequences with MIGS Standards: related news

GSC Aims to Unite Genome Sequences with MIGS Standards

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Nanotechnology, biomolecules, and light unite to "cook" cancer cells

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A Genome in Any Format

In a recent post, Andrew Yates asked, "How much data is a human genome?" He then did a little math to show that an uncompressed diploid human genome would easily fit on two music CDs, if stored as a text file. That got Genetic Future's Daniel MacArthur thinking. There are, he says, other formats that a human genome could be stored in, including as images from an Illumina machine. In that format, a genome with 30x coverage would take up about 28.80 terabytes. Also, if the sequence data is stored as a Sequence Read Format file, the storage space'll top out at 1.98 terabytes.

A damn cool open source tool called NEDI

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Me and my genome

BACK in 2002, before the $3 billion Human Genome Project was even complete, some biologists began to talk of sequencing the entire genome of any individual for just $1000. While DNA sequencing is getting ever cheaper and faster, we are not quite there yet: about a tenth of the human genome remains impossible to sequence with existing methods.

Sequenom Certifies McGill University and Genome Quebec Innovation Centre as First Center of Excellence

a leading provider of genetic analysis solutions, and Genome Quebec today announced that the McGill University and Genome Quebec Innovation Centre has become the first Center of Excellence certified by Sequenom for genotyping technology. The Center of Excellence certification is a collaborative partner relationship aimed at ensuring high-quality data available from genotyping application using the Sequenom MassARRAY(R) system performed at Genome Quebec.

OECD issues final report for nanotechnology standards workshop

(Nanowerk News) The International Workshop on Documentary Standards for Measurement and Characterisation in Nanotechnologies was held February 26-28, 2008 at the National Institute of Standards and Technology, Gaithersburg (USA), in co-ordination with ISO, IEC, NIST and the OECD. The participants discussed the development, efficacy, harmonisation and uptake of documentary standards broadly relevant to the field of measurement and characterisation for nanotechnologies.

Sequenom Certifies McGill University and Genome Quebec Innovation Centre as First Center of Excellence

SAN DIEGO & MONTREAL (Business Wire) -- Sequenom, Inc. (NASDAQ: SQNM), a leading provider of genetic analysis solutions, and Genome Quebec today announced that the McGill University and Genome Quebec Innovation Centre has become the first Center of Excellence certified by Sequenom for genotyping technology. The Center of Excellence certification is a collaborative partner relationship aimed at ensuring high-quality data available from genotyping application using the Sequenom MassARRAY(R) system performed at Genome Quebec.

Max-Planck Institute publishes Neanderthal mitochondrial genome sequence

Singapore, August 12, 2008: Researchers led by the Max-Planck Institute for Evolutionary Anthropology in Leipzig, Germany have published the complete Neanderthal mitochondrial genome sequence. The mitochondrial genome was generated using the 454 Sequencing technology to 35-fold redundancy, facilitating a detailed comparison against known human mitochondrial genomes and an analysis of recent human evolution. The study, entitled “A complete Neanderthal mitochondrial genome sequence determined by high-throughput sequencing” appears in the journal Cell.

IE8 Breaking Microsoft's Web Standards Promise?

An anonymous reader points out a story in The Register by Opera Software CTO Hakon Lie which tells the story of how Microsoft's interoperability promise for IE8 seems to have been broken in less than six months. Quoting: "In March, Microsoft announced that their upcoming Internet Explorer 8 would: use its most standards compliant mode, IE8 Standards, as the default. Note the last word: default. Microsoft argued that, in light of their newly published interoperability principles, it was the right thing to do. This declaration heralded an about-face and was widely praised by the web standards community; people were stunned and delighted by Microsoft's promise. This week, the promise was broken."

Roche's 454 Sequencing System Used to Determine the Complete Neanderthal Mitochondrial Genome, Establishing When Humans and Neanderthals Diverged

BRANFORD, Conn.--(BUSINESS WIRE)--Aug 8, 2008 - Researchers led by the Max-Planck Institute for Evolutionary Anthropology in Leipzig, Germany have published the complete Neanderthal mitochondrial genome sequence. The mitochondrial genome was generated using the 454 Sequencing technology to 35-fold redundancy, facilitating a detailed comparison against known human mitochondrial genomes and an analysis of recent human evolution. The study, entitled "A complete Neanderthal mitochondrial genome sequence determined by high-throughput sequencing" appears today in the journal Cell.

deCODE and SGENE Consortium Discover Deletions in the Human Genome Linked to Risk of Schizophrenia

REYKJAVIK, Iceland, July 30 /PRNewswire-FirstCall/ -- In a major paper published today in the online edition of the journal Nature, scientists from deCODE genetics (Nasdaq: DCGN) and the University of Iceland, along with academic colleagues from the deCODE-led European SGENE consortium, China and the United States, report the discovery of three rare deletions in the human genome that confer risk of schizophrenia. Such deletions are gaps in the normal sequence of the genome that can arise spontaneously during the recombination or reshuffling of the genome that takes place in the creation of sperm and eggs. The deletions reported in today's study are located on chromosomes 1q21, 15q11 and 15q13, and confer, respectively, 3, 15 and 12 times greater than average risk of schizophrenia.

deCODE and SGENE Consortium Discover Deletions in the Human Genome Linked to Risk of Schizophrenia

REYKJAVIK, Iceland, July 30, 2008 /PRNewswire-FirstCall via COMTEX/ -- DCGN | Quote | Chart | News | PowerRating -- In a major paper published today in the online edition of the journal Nature, scientists from deCODE genetics (Nasdaq: DCGN | Quote | Chart | News | PowerRating) and the University of Iceland, along with academic colleagues from the deCODE-led European SGENE consortium, China and the United States, report the discovery of three rare deletions in the human genome that confer risk of schizophrenia. Such deletions are gaps in the normal sequence of the genome that can arise spontaneously during the recombination or reshuffling of the genome that takes place in the creation of sperm and eggs. The deletions reported in today's study are located on chromosomes 1q21, 15q11 and 15q13, and confer, respectively, 3, 15 and 12 times gre

US Department Of Energy Joint Genome Institute Announces New Genome Sequencing Projects

Walnut Creek, CA - In the continuing effort to tap the vast, unexplored reaches of the earth's microbial and plant domains for bioenergy and environmental applications, the DOE Joint Genome Institute (DOE JGI) has announced its latest portfolio of DNA sequencing projects that it will undertake in the coming year. The 44 projects, culled from nearly 150 proposals received through the Community Sequencing Program (CSP), represent over 60 billion nucleotides of data to be generated through this biodiversity sampling campaign—roughly the equivalent of 20 human genomes.

Tricks of DNA Repair

Duke University Medical Center and NIH researchers have found that repeat-associated double-strand breaks can reshape the genome. In watching how DNA repairs itself in yeast after being broken by radiation, the scientists found a high level of recombination in repeated regions of the genome. "We have been able to show with yeast that these repeated sequences allow the formation of new types of chromosomes (chromosome aberrations), and represent one important way of diversifying the genome," says Lucas Argueso at ScienceDaily.

Genome Prairie announces new president and CEO

Dr. Arnold Naimark, chair of Genome Prairie's board of directors, appoints Dr. Wilf Keller as the new president and CEO of Genome Prairie.

Genome sequencing study reveals new genetic typhoid fever signatures

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Cocoa Genome To Be Sequenced: May Benefit Millions Of Farmers, Help Sustain World's Chocolate Supply

The United States Department of Agriculture-Agricultural Research Service (USDA-ARS), Mars, Incorporated, and IBM intend to apply their scientific resources to sequence and analyze the entire cocoa genome. Sequencing the cocoa genome is a significant scientific step that may allow more directed breeding of cocoa plants and perhaps even enhance the quality of cocoa, the key ingredient in chocolate.

The Rat Genome Database Publishes Rat Signaling Pathway Collection Made with Ariadne Pathway Studio

ROCKVILLE, Md., July 23, 2008 – Ariadne announced today that the Rat Genome Database at the Medical College of Wisconsin has published a rat signaling pathway diagram collection created with Ariadne Pathway Studio. The pathways are available on the Rat Genome Database website. Each diagram is interactive, linked to detailed information about proteins, relationships, and related pathways.

Neanderthal Mitochondrial Genome Sequence Published

Researchers led by the Max-Planck Institute for Evolutionary Anthropology in Leipzig, Germany have published the complete Neanderthal mitochondrial genome sequence. The mitochondrial genome was generated using the 454 Sequencing technology to 35-fold redundancy, facilitating a detailed comparison against known human mitochondrial genomes and an analysis of recent human evolution.

Me and my genome

Some biologists hope that it will be possible to sequence the entire genome of any individual. While DNA sequencing is progressing fast, a tenth of the human genome remains impossible to sequence with existing methods. This obstacle has not discouraged companies from commercialising their DNA research. 23andMe and deCodeMe offer clients a personal DNA read-outs for about $US1,000. In April 2008, Navigenics launched a similar package for $US2,500 and a yearly fee of $US250. The package includes access to "genetic counsellors" and the storage of one's DNA until it can be re-analysed as the technology improves

Intel invests in genome-sequencing outfit

A BUNCH of fad-wadded companies is to bung $100 million at a start-up that aims to be able to deliver individuals' DNA sequence a genome in a matter of minutes.


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