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First sequence-based map of large-scale structural variation across the human genome

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CALANDO PHARMACEUTICALS DOSES FIRST PATIENT IN siRNA PHASE I

Calando Pharmaceuticals doses first patient with CALAA-01, a targeted nanoparticle therapeutic. This represents the first siRNA therapeutic to enter the clinic in oncology and the first targeted delivery of any RNAi product. PASADENA, Calif.-- June 2, 2008- Calando Pharmaceuticals, a majority-owned subsidiary of Arrowhead Research Corporation (NASDAQ: ARWR), announced today that the first patient has successfully completed the first dosing cycle (four doses over two weeks) of CALAA-01 in the first clinical trial using systemically-delivered siRNA to treat cancer. CALAA-01 is a targeted nanoparticle, comprised of a proprietary, non-chemically-modified siRNA against the M2 subunit of ribonucleotide reductase-a clinically-validated cancer target-formulated with Calando's proprietary RONDEL(TM) (RNAi/Oligonucleotide Nanoparticle Delivery) pol

Sea Life Safari Makes a Splash on Xbox LIVE Arcade

LOS ANGELES, June 18 /PRNewswire/ -- Sierra Online, a division of Vivendi Games, dives into the wonders of the deep with the launch of Sea Life Safari(TM) for Xbox LIVE(R) Arcade for the Xbox 360(R) video game and entertainment system from Microsoft. In the Sea Life Safari game, players are cast into the role of a deep sea photographer challenged with capturing the most incredible pictures of wild sea creatures.

Select Comfort web sales toss and turn in the first quarter

In the first quarter, web sales dropped by 19.1% to $12.3 million from $15.2 million in the first quarter of 2007. Select Comfort, No. 175 in the Internet Retailer Top 500 Guide, also posted a net loss of $7.1 million on sales of $168.2 million, compared with net income of $10.7 million on revenue of $216.5 million in the first quarter of 2007. Comparable store sales dropped year-over-year by 25%. The web accounted for about 7% of total sales in the first quarter.

Phoenix Spacecraft BeamsHome First Images of Martian Arctic

PASADENA, Calif. - NASA's Phoenix Mars Lander has returned its first images from the surface of Mars, showing that the probe's vital solar arrays have successfully deployed and giving scientists their first up-close glimpse of the Martian arctic surface. Phoenix landed in a northern polar region of Mars called Vastitas Borealis late Sunday, with mission controllers here at NASA's Jet Propulsion Laboratory (JPL) receiving their first signals from the spacecraft at about 7:53 p.m. EDT (2353 GMT). The first image Phoenix was instructed to take was of its solar arrays...

Remarks by the First Lady at the Americans for the Arts and Smithsonian Institution Luncheon

NATIONAL GASOLINE BOYCOTT: BitMar.com Prepares to Reach Almost 300 Million Americans to Organize the First, Largest, Strategic, and Fully Orchestrated Gas Boycott

Port City Java(R) Announces Same Corporate Unit Sales Increase of 3.65% During First Six Months of 2008; Signs First Lease in Jordan

Port City Java(R) Announces Same Corporate Unit Sales Increase of 3.65% During First Six Months of 2008; Signs First Lease in Jordan

Port City Java(R) Announces Same Corporate Unit Sales Increase of 3.65% During First Six Months of 2008; Signs First Lease in Jordan

Port City Java(R) Announces Same Corporate Unit Sales Increase of 3.65% During First Six Months of 2008; Signs First Lease in Jordan

Route 66 Drives onto DVD this Summer

The classic 1960s television series, Route 66, is coming to DVD this summer. The eight-disc collector set, Route 66 Complete First Season Television Series, from Roxbury Entertainment and Infinity Entertainment Group, also features original TV commercials, filmographies of the stars and special guests, and a Corvette photo gallery. It will hit stores August 5.

Phytoplankton Bloom Erupts in the North Sea

Usually the North Sea conjures up cold and gloomy visions. But as the stunning image above shows, this isn't always the case. ESA's Envisat captured vast green swirls of phytoplankton bloom drifting in the North Sea currents on May 7th 2008; spring has most definitely sprung for the Scottish waters. But how is this bright green bloom produced? What has stirred up all this activity? It seems that for a short time, the lush green landscape of Fife is matched by the sea-faring plankton off the UK coast…

Circuit City Stores, Inc. Reports First Quarter Results

today reported results for the first quarter ended May 31, 2008. "In the first quarter, we continued to see improvement in many of our operating performance measures," said Philip J. Schoonover, chairman, president and chief executive officer of Circuit City Stores, Inc. "We are rebuilding our selling culture and focusing on creating a good first and last impression with the customer. We have seen improved trends in our store close rate and in our services and accessories attachments, and we are delivering a better customer experience in our stores as evidenced by the upward trends in our third-party mystery shop scores. In short, the quarter represented improved execution and solid, steady progress towards our goals, and we expect to start to see year-over-year improvements in our financial results beginning in the second half of the yea

Was This the First CC Community-Edited Novel?

Odinson writes "In late 2005 I released a draft of a science fiction novel under the by-nc-nd CC license. I started accepting edits in the hope of polishing a manuscript for submission to a publisher. A publisher never materialized, but after thousands of comments the draft started getting really solid. So a couple of months ago I decided to buy an ISBN and sell hard copies from Lulu. While doing research for a press release, I was unable to uncover the first community-edited, CC-licensed work of fiction. I strongly suspect that my novel is the first. Can anybody point to a prior example? How about under other licenses? If someone has traveled this road before, I'd like to ask them how it went. I would also like to vet this question here before staking a claim to be the first.

Fla. man claims tea caused him to fail drug test

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Wash. dentist's staff saddles up to beat gas costs

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New Mexico couple call off home giveaway contest

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Barge floats 2-story home from Wash. to Canada

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Jackals, lizards, raptors delay flights in India

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Man gets Air Force leave extended for White Castle

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Man crashes into police gate, asks to be jailed

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